Funding Opp: CZI Deep Tissue Imaging RFA

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CZI Deep Tissue Imaging RFA


Sponsor: Chan Zuckerberg Initiative
Source: Private
Title of Funding OpportunityCZI Deep Tissue Imaging

Deadline: August 6, 2020 by 5 p.m. PST


Synopsis of offering:

The Chan Zuckerberg Initiative’s Imaging program seeks to enable researchers everywhere to visualize, measure, and analyze the biological processes underlying health and disease. CZI invites applications for its new Deep Tissue Imaging Request for Applications (RFA) to help support innovations in deep tissue imaging technology, focused on obtaining critical, high-resolution data at the cellular level.

This RFA supports the development of technologies that will allow researchers to view information at cellular resolution, in complex tissue and through skin and bone, in living organisms. Awards are $1 million in total over 2.5 years for each pilot project, and successful pilots will be eligible to apply for additional four-year follow-up grants.

More information here 


To meet the goals of catalyzing new ideas and inspiring innovative science, the Deep Tissue Imaging RFA is structured as a two-phased funding opportunity.

Phase 1: In the first phase, we invite letters of intent (LOI) where applicants will provide a short proposal detailing the current state-of-the-art technology they are working on and how their project advances this technology. ○ A subset of the LOI applicants will be invited to submit a full application for 2.5-year (30-month) pilot awards ($1 million total costs/award).

Phase 2: At the conclusion on the 2.5-year pilot period, successful pilot projects in Phase 1 will be eligible for application and evaluation for an extended 48-month grant award ($10 million total costs/award, or $2.5 million total costs/award/year), for a total of up to $11 million total over six-and-a-half years for the entirety of the project (Phase 1 and Phase 2). We anticipate awarding Phase 2 four-year grants to a subset of the eligible Phase 1 pilot projects.

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  • Applications may be submitted by non-profit and for-profit organizations, public and private institutions, such as colleges, universities, hospitals, laboratories, units of state and local government, companies, and eligible agencies of the federal government. As part of the application process, for-profit organizations may need to provide additional information on the charitable purposes of the proposal. Grants are not permitted to individuals; only to organizations.


Application Specifics: All applications must be completed and submitted through CZI’s online grants management portal at It is recommended that applicants familiarize themselves with this portal well in advance of the application deadline. Detailed application instructions are available on the Chan Zuckerberg Initiative website, as well as in the grants management portal.

More information here